Someone sent orders to assassinate Lupin! Will he survive or die trying!? After the intrepid Inspector Zenigata is reassigned from the Lupin case to destroying the international weapon smugglers Shot Shell, master thief Lupin the Third decides to help the old man get his old job back. To infiltrate Shot Shell, the gang "borrows" a nuclear Russian submarine and enlists the help of a nuclear physicist named Karen, who keeps suspiciously eyeing Lupin's partner Jigen. If that weren't enough, Zenigata's Interpol successor is an assassin with orders to take out the entire Lupin Gang!